2017-10-01

av K Magnusson · 2015 — that SATB2 is a sensitive and specific biomarker for colorectal cancer, staining 85% of all investigated tumors. Moreover, SATB2 in combination

Test ID SATB2 SATB2 Immunostain, Technical Component Only Advisory Information This test includes only technical performance of the stain (no pathologist interpretation is performed). SATB2 is a DNA-binding protein that interacts with DNA matrix attachment regions to alter gene expression by inducing local chromatin remodeling. In contrast to TBR1, SOX5, and FEZF2, SATB2 controls the expression profiles, migration, and connectivity of intracortical projection neurons ( Fig. 6.3) ( Alcamo et al., 2008; Britanova et al., 2008 ). SATB2, when used in combination with the marker Keratin 20, may identify more than 95% of colorectal carcinoma. It may also be used to differentiate rectal neuroendocrine tumors from other neuroendocrine tumors of the gastrointestinal tract. Interpretation.

When crossed with mice carrying loxP-flanked sequences of interest, floxed regions are excised in Satb2-expressing cells of the parabrachial nucleus (PBN). Expression of SATB2 (FLJ21474, KIAA1034) in lymph node tissue. Antibody staining with HPA001042, HPA029543, CAB023669, CAB062562, CAB067751, CAB068229, CAB068230 and CAB068231 in immunohistochemistry. Complete information for SATB2 gene (Protein Coding), SATB Homeobox 2, including: function, proteins, disorders, pathways, orthologs, and expression. GeneCards - The Human Gene Compendium Triple Stain PSA PSAP/HPAPMLH1 PSMA PTH RCC1 S100 ESCC (Esophageal) S100p SALL4 SATB2(PASD+PAS) Serotonin. Reticulin SF1 SMA SMMHC Smoothelin Somatostatin SSTR2 (Somatostatin Receptor, Type 2) SOX2 SOX10 SOX11 STAT6 Surfactant TCL1 TCR BetaF1 TCR Delta Thrombomodulin (TM) Thyroglobulin (TGB) TIA1 Test Code SATB2 SATB2 Immunostain, Technical Component Only Advisory Information This test includes only technical performance of the stain (no pathologist interpretation is performed).

Test Code SATB2 SATB2 Immunostain, Technical Component Only Advisory Information This test includes only technical performance of the stain (no pathologist interpretation is performed).

A nuclear localizing signal (NLS) directs expression of cre to the nucleus. Three quarters of gastric primaries stain for CDX2 and only rare examples stain for SATB2.

The epithelial marker cytokeratin 20 (CK20) stains positive with immunohistochemistry in a vast majority of MCCs. The expression of the special AT-rich sequence-binding protein (SATB2) was analyzed in MCC (n = 20) together with other forms of skin cancer and neuroendocrine tumors (n = 51) using immunohistochemistry.

Special AT-rich sequence-binding protein 2 (SATB2) Authors: Angela M.Y. Chan, M.Sc., Emeka Enwere, Ph.D. Topic Completed: 1 February 2017. Minor changes: 25 February 2021. Copyright: 2017-2021, PathologyOutlines.com, Inc. PubMed Search: Special AT-rich sequence-binding protein 2 OR SATB2.

In normal tissues, strong nuclear SATB2 expression is observed in essentially all glandular cells lining the lower gastrointestinal tract, including the appendix, colon, and rectum. SATB2 is also The epithelial marker cytokeratin 20 (CK20) stains positive with immunohistochemistry in a vast majority of MCCs.
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Special Stains Group I 88312. Primary Demonstration of: Fite stain. Stains for mycobacteria May 7, 2019 Transduction.

(2014) identified 3 different functional enhancing cis-regulatory elements (CREs) in the gene desert between the PLCL1 and SATB2 genes, 3-prime to SATB2. This test includes only technical performance of the stain (no pathologist interpretation is performed). If diagnostic consultation by a pathologist is required order PATHC / Pathology Consultation. The positive and negative controls are verified as showing appropriate immunoreactivity.
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Triple Stain PSA PSAP/HPAPMLH1 PSMA PTH RCC1 S100 ESCC (Esophageal) S100p SALL4 SATB2(PASD+PAS) Serotonin. Reticulin SF1 SMA SMMHC Smoothelin Somatostatin SSTR2 (Somatostatin Receptor, Type 2) SOX2 SOX10 SOX11 STAT6 Surfactant TCL1 TCR BetaF1 TCR Delta Thrombomodulin (TM) Thyroglobulin (TGB) TIA1

Prestige Antibodies® developed for immunohistochemistry based expression profiling are recommended to be used according to the standard IHC staining SATB2 stains colonic and osteogenic cells and their neoplasms. Stain Only. Turnaround Time. 24 hours. *The CPT codes provided with our test descriptions Feb 25, 2021 SATB2 is a biomarker for colorectal cancer, 85% of all CRC patients are positive for SATB2 and other cancer types rarely display SATB2 Anti-SATB2 Antibody (SATBA4B10): sc-81376 · Can I use this mouse monoclonal antibody for immunohistochemical staining of mouse tissue?